BDBM50318633 3-benzenesulfonyl-8-piperazin-1-ylquinoline::CHEMBL1083390::SB-742457

SMILES: O=S(=O)(c1ccccc1)c1cnc2c(cccc2c1)N1CCNCC1

InChI Key: InChIKey=JJZFWROHYSMCMU-UHFFFAOYSA-N

Data: 23 KI  4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50318633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Rat)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Rat)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 2A (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 1A (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		997	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		997	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		2.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		2.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM50318633 (SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair