BDBM50318704 CHEMBL1084519::Ethyl 5-Amino-2-methyl-6,7,8,9,10,11-hexahydrocycloocta-[b][1,8]naphthyridine-3-carboxylate

SMILES CCOC(=O)c1cc2c(N)c3CCCCCCc3nc2nc1C

InChI Key InChIKey=LQZDBOQHVFTGOE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50318704   

TargetCholinesterase(Equus caballus (Horse))
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50318704(CHEMBL1084519 | Ethyl 5-Amino-2-methyl-6,7,8,9,10,...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50318704(CHEMBL1084519 | Ethyl 5-Amino-2-methyl-6,7,8,9,10,...)
Affinity DataIC50:  400nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50318704(CHEMBL1084519 | Ethyl 5-Amino-2-methyl-6,7,8,9,10,...)
Affinity DataIC50:  400nMAssay Description:Displacement of propidium iodide from AChE in bovine erythrocytes after 15 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Universidad Autonoma De Madrid

Curated by ChEMBL
LigandPNGBDBM50318704(CHEMBL1084519 | Ethyl 5-Amino-2-methyl-6,7,8,9,10,...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of AChE in human erythrocytes by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed