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BDBM50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15

SMILES: CN(C)CCCN1c2ccccc2Sc3c1cc(cc3)Cl

InChI Key: InChIKey=ZPEIMTDSQAKGNT-UHFFFAOYSA-N

Data: 239 KI 79 IC50 4 Kd 9 EC50

PDB links: 10 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 331 hits for monomerid = 50001888
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proteasome subunit alpha type-6 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.48E+4	n/a	n/a	7.5	37
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Proteasome subunit alpha type-6 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	9.90E+3	n/a	n/a	7.5	37
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NADPH oxidase 1 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Spike glycoprotein (MERS-CoV)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	9.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Spike glycoprotein (SARS-CoV)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Orf1a protein (MERS-CoV)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (SARS-CoV)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (HCoV-229E)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
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Orf1a protein (MERS-CoV)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	9.51E+3	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (SARS-CoV)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cys-loop ligand-gated ion channel (Pectobacterium chrysanthemi)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.58E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Major prion protein (Mouse)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rat)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
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Sphingomyelin phosphodiesterase (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Rat)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.15	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Bovine)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Rabbit)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde oxidase (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific histone demethylase 1A (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Trypanothione reductase (Trypanosoma cruzi)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Calmodulin-1 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde oxidase (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde oxidase 1 (Rabbit)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aldehyde oxidase (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
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Calmodulin-1 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rat)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A/1B/1D/1F (Rat)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
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Serotonin 2 (5-HT2) receptor (Rat)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	372	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Major prion protein (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 1 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cruzipain (Trypanosoma cruzi)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.84E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cruzipain (Trypanosoma cruzi)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.89E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Pleiotropic ABC efflux transporter of multiple drugs (Baker's yeast)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50001888 ([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
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