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BDBM50318935 4-(2,4-diethyl-1-(3-hydroxypropyl)-1H-pyrrol-3-yloxy)benzonitrile::CHEMBL1083453

SMILES: CCc1cn(CCCO)c(CC)c1Oc1ccc(cc1)C#N

InChI Key: InChIKey=WZURIUYCIOUPEI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50318935   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM50318935
PNG
(4-(2,4-diethyl-1-(3-hydroxypropyl)-1H-pyrrol-3-ylo...)
Show SMILES CCc1cn(CCCO)c(CC)c1Oc1ccc(cc1)C#N
Show InChI InChI=1S/C18H22N2O2/c1-3-15-13-20(10-5-11-21)17(4-2)18(15)22-16-8-6-14(12-19)7-9-16/h6-9,13,21H,3-5,10-11H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 204n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant progesterone receptor expressed in CHO-MMTV-beta-lactamase cells assessed as inhibition of progesterone-indu...


Bioorg Med Chem Lett 20: 3384-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.018
BindingDB Entry DOI: 10.7270/Q2NK3F6K
More data for this
Ligand-Target Pair