BDBM50319163 8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine::CHEMBL1085374

SMILES: CCCc1nc(c2n1c3c(ccc(n3)OC)nc2NS(=O)(=O)C)C

InChI Key: InChIKey=WYHTXPAKFZNNJB-UHFFFAOYSA-N

Data: 12 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50319163   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	561	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-dependent 3',5'-cyclic phosphodiesterase (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50319163 (8-Methoxy-3-methyl-4-methylsulfonylamino-1-propyl-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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