BDBM50319165 2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrido[3,2-e]pyrazine::3,4-Dimethyl-8-methoxy-1-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine::CHEMBL1086110

SMILES: CCCc1nc(c2n1c3c(ccc(n3)OC)nc2C)C

InChI Key: InChIKey=YNADXFWEXJTQSZ-UHFFFAOYSA-N

Data: 29 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50319165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Bovine)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	779	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	919	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM50319165 (2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair