BDBM50319243 2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-4-yl)-2-methylpropanamido)benzoicacid::CHEMBL1086104

SMILES CC(Cc1cnn(c1C)-c1ccc(O)cc1)C(=O)Nc1ccccc1C(O)=O

InChI Key InChIKey=XUZKZJUMJQXACN-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319243   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50319243(2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-4-yl...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50319243(2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-4-yl...)
Affinity DataIC50:  77nMAssay Description:Displacement of [3H]niacin from GRP109A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50319243(2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-4-yl...)
Affinity DataEC50:  1.10E+3nMAssay Description:Displacement of [3H]niacin from GRP109A receptor in presence of 4% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50319243(2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-4-yl...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed