BDBM50319287 (+/-)-5-fluoro-2-(4-(3-(hexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl)propoxy)-2-methylphenyl)-4-methyl-1H-benzo[d]imidazole::CHEMBL1083098

SMILES Cc1cc(OCCCN2CC3CCNC3C2)ccc1-c1nc2ccc(F)c(C)c2[nH]1

InChI Key InChIKey=GWXYGVYIVWODLJ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50319287   

TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50319287((+/-)-5-fluoro-2-(4-(3-(hexahydropyrrolo[3,4-b]pyr...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50319287((+/-)-5-fluoro-2-(4-(3-(hexahydropyrrolo[3,4-b]pyr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human histamine H4 receptor in SK-N-MC cells assessed as forskolin-stimulated cAMP release preincubated for 10 mins before forsko...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed