BDBM50319423 3-Methoxy-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-morpholin-4-yl-ethoxy)-phenyl]-benzamide::CHEMBL1084617

SMILES COc1cccc(c1)C(=O)Nc1ccc(OCCN2CCOCC2)c(c1)-c1ccnn1C

InChI Key InChIKey=ZEOQUKRCASTCFR-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50319423   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319423(3-Methoxy-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-mor...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319423(3-Methoxy-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-mor...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319423(3-Methoxy-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-mor...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2B receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319423(3-Methoxy-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-mor...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50319423(3-Methoxy-N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-mor...)
Affinity DataIC50:  5.20nMAssay Description:Inverse agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as inhibition of inositol phosphate accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed