BDBM50319926 2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo-4H-chromen-8-yl)dibenzo[b,d]thiophen-1-yl)acetamide::CHEMBL1086377::KU-0060648

SMILES: CCN1CCN(CC(=O)Nc2ccc(-c3cccc4c3oc(cc4=O)N3CCOCC3)c3sc4ccccc4c23)CC1

InChI Key: InChIKey=AATCBLYHOUOCTO-UHFFFAOYSA-N

Data: 18 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50319926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine-protein kinase ATM (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase ATR (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA-dependent protein kinase catalytic subunit (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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DNA-dependent protein kinase catalytic subunit (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	136	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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DNA-dependent protein kinase catalytic subunit (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Human)	BDBM50319926 (2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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