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BDBM50320482 1,1,1-trifluoro-3-(3-(((3-(3-methoxyphenoxy)phenyl)(3,3,3-trifluoro-2-hydroxypropyl)amino)methyl)phenoxy)propan-2-ol::CHEMBL1165170

SMILES: COc1cccc(Oc2cccc(c2)N(CC(O)C(F)(F)F)Cc2cccc(OCC(O)C(F)(F)F)c2)c1

InChI Key: InChIKey=ZMZIGPRBVSUHQT-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320482   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cholesteryl ester transfer protein


(Oryctolagus cuniculus)
BDBM50320482
PNG
(1,1,1-trifluoro-3-(3-(((3-(3-methoxyphenoxy)phenyl...)
Show SMILES COc1cccc(Oc2cccc(c2)N(CC(O)C(F)(F)F)Cc2cccc(OCC(O)C(F)(F)F)c2)c1
Show InChI InChI=1/C26H25F6NO5/c1-36-19-7-4-10-22(13-19)38-21-9-3-6-18(12-21)33(15-23(34)25(27,28)29)14-17-5-2-8-20(11-17)37-16-24(35)26(30,31)32/h2-13,23-24,34-35H,14-16H2,1H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Al-Zaytoonah Private University of Jordan

Curated by ChEMBL


Assay Description
Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assay


Eur J Med Chem 45: 1598-617 (2010)


Article DOI: 10.1016/j.ejmech.2009.12.070
BindingDB Entry DOI: 10.7270/Q2VQ32VS
More data for this
Ligand-Target Pair