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BDBM50321133 (4-(4-fluorobenzoyl)piperidin-1-yl)(4-morpholinophenyl)methanone::CHEMBL1163966

SMILES: Fc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(cc1)N1CCOCC1

InChI Key: InChIKey=ZEDUJYKZFCQXOW-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321133   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (Human))
BDBM50321133
PNG
((4-(4-fluorobenzoyl)piperidin-1-yl)(4-morpholinoph...)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C23H25FN2O3/c24-20-5-1-17(2-6-20)22(27)18-9-11-26(12-10-18)23(28)19-3-7-21(8-4-19)25-13-15-29-16-14-25/h1-8,18H,9-16H2
PDB
MMDB

Reactome pathway
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UniProtKB/SwissProt
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DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.35E+4n/an/an/an/an/an/a



AstraZeneca PLC

Curated by ChEMBL


Assay Description
Inhibition of human 11beta-HSD1 by competitive binding assay


Bioorg Med Chem 18: 4405-14 (2010)


Article DOI: 10.1016/j.bmc.2010.04.077
BindingDB Entry DOI: 10.7270/Q2GB247Z
More data for this
Ligand-Target Pair