BDBM50321133 (4-(4-fluorobenzoyl)piperidin-1-yl)(4-morpholinophenyl)methanone::CHEMBL1163966

SMILES: Fc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(cc1)N1CCOCC1

InChI Key: InChIKey=ZEDUJYKZFCQXOW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50321133 ((4-(4-fluorobenzoyl)piperidin-1-yl)(4-morpholinoph...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ccc(cc1)N1CCOCC1 Show InChI InChI=1S/C23H25FN2O3/c24-20-5-1-17(2-6-20)22(27)18-9-11-26(12-10-18)23(28)19-3-7-21(8-4-19)25-13-15-29-16-14-25/h1-8,18H,9-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca PLC Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 by competitive binding assay				Bioorg Med Chem 18: 4405-14 (2010) Article DOI: 10.1016/j.bmc.2010.04.077 BindingDB Entry DOI: 10.7270/Q2GB247Z
					More data for this Ligand-Target Pair