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BDBM50321405 3-(4-(3-chlorophenyl)piperazin-1-yl)-N-((4-phenyl-2-propyloxazol-5-yl)methyl)propan-1-amine::CHEMBL1170570

SMILES: CCCc1nc(c(CNCCCN2CCN(CC2)c2cccc(Cl)c2)o1)-c1ccccc1

InChI Key: InChIKey=DLCXKRUOCYZVCV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321405   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated T-type calcium channel


(Homo sapiens (Human))
BDBM50321405
PNG
(3-(4-(3-chlorophenyl)piperazin-1-yl)-N-((4-phenyl-...)
Show SMILES CCCc1nc(c(CNCCCN2CCN(CC2)c2cccc(Cl)c2)o1)-c1ccccc1
Show InChI InChI=1S/C26H33ClN4O/c1-2-8-25-29-26(21-9-4-3-5-10-21)24(32-25)20-28-13-7-14-30-15-17-31(18-16-30)23-12-6-11-22(27)19-23/h3-6,9-12,19,28H,2,7-8,13-18,20H2,1H3
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.75E+3n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of T-type CaV3.1 channel expressed in HEK293 cells assessed as inhibition of calcium current by automated patch-clamp assay


Bioorg Med Chem Lett 20: 4219-22 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.030
BindingDB Entry DOI: 10.7270/Q2PN96KW
More data for this
Ligand-Target Pair