BDBM50321544 CHEMBL1172276::N-(7-(N-ethylacetamido)-4-methoxybenzo[d]thiazol-2-yl)-4-((2-oxopyrrolidin-1-yl)methyl)benzamide

SMILES CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(CN4CCCC4=O)cc3)sc12

InChI Key InChIKey=DLTPQCCVNJKPLX-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321544   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321544(CHEMBL1172276 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2B receptor expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321544(CHEMBL1172276 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]-ZM241385 from human adenosine A2A receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321544(CHEMBL1172276 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50321544(CHEMBL1172276 | N-(7-(N-ethylacetamido)-4-methoxyb...)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of adenosine-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed