BindingDB logo
myBDB logout

BDBM50321751 5-Chloro-2-(2-methylphenyl)-4H-benzo[d][1,3]oxazin-4-one::CHEMBL1172306

SMILES: Cc1ccccc1-c1nc2cccc(Cl)c2c(=O)o1

InChI Key: InChIKey=DQZSVPWWXDDJAX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB:
Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50321751   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukocyte elastase


(Homo sapiens (Human))
BDBM50321751
PNG
(5-Chloro-2-(2-methylphenyl)-4H-benzo[d][1,3]oxazin...)
Show SMILES Cc1ccccc1-c1nc2cccc(Cl)c2c(=O)o1
Show InChI InChI=1S/C15H10ClNO2/c1-9-5-2-3-6-10(9)14-17-12-8-4-7-11(16)13(12)15(18)19-14/h2-8H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 48.8n/an/an/an/an/an/a



Chang Gung University

Curated by ChEMBL


Assay Description
Inhibition of human leukocyte elastase after 2 mins by ELISA


Eur J Med Chem 45: 3111-5 (2010)


Article DOI: 10.1016/j.ejmech.2010.03.046
BindingDB Entry DOI: 10.7270/Q2251JCW
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50321751
PNG
(5-Chloro-2-(2-methylphenyl)-4H-benzo[d][1,3]oxazin...)
Show SMILES Cc1ccccc1-c1nc2cccc(Cl)c2c(=O)o1
Show InChI InChI=1S/C15H10ClNO2/c1-9-5-2-3-6-10(9)14-17-12-8-4-7-11(16)13(12)15(18)19-14/h2-8H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 57.1n/an/an/an/an/an/a



Chang Gung University

Curated by ChEMBL


Assay Description
Inhibition of human neutrophil elastase after 30 mins by ELISA


Eur J Med Chem 45: 3111-5 (2010)


Article DOI: 10.1016/j.ejmech.2010.03.046
BindingDB Entry DOI: 10.7270/Q2251JCW
More data for this
Ligand-Target Pair