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BDBM50321927 5-(Cyclohexylmethoxy)-3-((3-hydroxy-1-phenylpropylamino)methyl)-4H-chromen-4-one::CHEMBL1172767

SMILES: OCCC(NCc1coc2cccc(OCC3CCCCC3)c2c1=O)c1ccccc1

InChI Key: InChIKey=DMZXOAXJDLQROU-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321927   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-5


(Mus musculus)
BDBM50321927
PNG
(5-(Cyclohexylmethoxy)-3-((3-hydroxy-1-phenylpropyl...)
Show SMILES OCCC(NCc1coc2cccc(OCC3CCCCC3)c2c1=O)c1ccccc1
Show InChI InChI=1S/C26H31NO4/c28-15-14-22(20-10-5-2-6-11-20)27-16-21-18-31-24-13-7-12-23(25(24)26(21)29)30-17-19-8-3-1-4-9-19/h2,5-7,10-13,18-19,22,27-28H,1,3-4,8-9,14-17H2
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of interleukin-5 in mouse Y16 cells


Bioorg Med Chem 18: 4625-9 (2011)


Article DOI: 10.1016/j.bmc.2010.05.028
BindingDB Entry DOI: 10.7270/Q2B8593F
More data for this
Ligand-Target Pair