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BDBM50321952 9-benzyl-N-(4-methoxyphenyl)-2-(piperazin-1-yl)-9H-purin-6-amine::CHEMBL1173031

SMILES: COc1ccc(Nc2nc(nc3n(Cc4ccccc4)cnc23)N2CCNCC2)cc1

InChI Key: InChIKey=FSIMBDCCPGXLPN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321952   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50321952
PNG
(9-benzyl-N-(4-methoxyphenyl)-2-(piperazin-1-yl)-9H...)
Show SMILES COc1ccc(Nc2nc(nc3n(Cc4ccccc4)cnc23)N2CCNCC2)cc1
Show InChI InChI=1S/C23H25N7O/c1-31-19-9-7-18(8-10-19)26-21-20-22(28-23(27-21)29-13-11-24-12-14-29)30(16-25-20)15-17-5-3-2-4-6-17/h2-10,16,24H,11-15H2,1H3,(H,26,27,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition cSRC


Bioorg Med Chem 18: 4615-24 (2011)


Article DOI: 10.1016/j.bmc.2010.05.032
BindingDB Entry DOI: 10.7270/Q26H4JCQ
More data for this
Ligand-Target Pair