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BDBM50322043 (2S,2'S)-diethyl 2,2'-((5-(2-amino-5-isobutylthiazol-4-yl)furan-2-yl)phosphoryl)bis(azanediyl)dipropanoate::CHEMBL259771::MB06322::ethyl (2S)-2-[({5-[2-amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl}({[(2S)-1-ethoxy-1-oxopropan-2-yl]amino})phosphoryl)amino]propanoate

SMILES: CCOC(=O)[C@H](C)NP(=O)(N[C@@H](C)C(=O)OCC)c1ccc(o1)-c1nc(N)sc1CC(C)C

InChI Key: InChIKey=BYKBUQDQTLDNLE-KBPBESRZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322043   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fructose-1,6-bisphosphatase 1 (FBPase)


(Homo sapiens (Human))
BDBM50322043
PNG
((2S,2'S)-diethyl 2,2'-((5-(2-amino-5-isobutylthiaz...)
Show SMILES CCOC(=O)[C@H](C)NP(=O)(N[C@@H](C)C(=O)OCC)c1ccc(o1)-c1nc(N)sc1CC(C)C
Show InChI InChI=1S/C21H33N4O6PS/c1-7-29-19(26)13(5)24-32(28,25-14(6)20(27)30-8-2)17-10-9-15(31-17)18-16(11-12(3)4)33-21(22)23-18/h9-10,12-14H,7-8,11H2,1-6H3,(H2,22,23)(H2,24,25,28)/t13-,14-/m0/s1
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n/an/a 10n/an/an/an/an/an/a



Daiichi Sankyo Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human FBase


Bioorg Med Chem 18: 5346-51 (2010)


Article DOI: 10.1016/j.bmc.2010.05.041
BindingDB Entry DOI: 10.7270/Q2TB17V0
More data for this
Ligand-Target Pair