BindingDB logo
myBDB logout

BDBM50322184 3-(4-ethylphenylsulfonyl)-N-phenethylthieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine::CHEMBL1173570

SMILES: CCc1ccc(cc1)S(=O)(=O)c1nnn2c3ccsc3c(NCCc3ccccc3)nc12

InChI Key: InChIKey=BOCKHYZDGOPDGR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322184   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))
BDBM50322184
PNG
(3-(4-ethylphenylsulfonyl)-N-phenethylthieno[2,3-e]...)
Show SMILES CCc1ccc(cc1)S(=O)(=O)c1nnn2c3ccsc3c(NCCc3ccccc3)nc12
Show InChI InChI=1S/C23H21N5O2S2/c1-2-16-8-10-18(11-9-16)32(29,30)23-22-25-21(24-14-12-17-6-4-3-5-7-17)20-19(13-15-31-20)28(22)27-26-23/h3-11,13,15H,2,12,14H2,1H3,(H,24,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.05E+3n/an/an/an/an/an/a



Chemical Diversity Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production


Bioorg Med Chem 18: 5282-90 (2010)


Article DOI: 10.1016/j.bmc.2010.05.051
BindingDB Entry DOI: 10.7270/Q2F190QT
More data for this
Ligand-Target Pair