BDBM50322325 (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(3-fluorophenyl)acrylate::CHEMBL1172951

SMILES Cc1ncc(n1CCOC(=O)\C=C\c1cccc(F)c1)[N+]([O-])=O

InChI Key InChIKey=CYFPQVFLFVUCKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322325   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322325((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human recombinant His6x-tagged EGFR autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322325((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(...)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of human recombinant His6x-tagged HER2 autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed