BDBM50322338 (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(2-fluorophenyl)acrylate::CHEMBL1172877

SMILES Cc1ncc(n1CCOC(=O)\C=C\c1ccccc1F)[N+]([O-])=O

InChI Key InChIKey=NRCCVAAPDNQWEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322338   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322338((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(2...)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of human recombinant His6x-tagged EGFR autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50322338((E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(2...)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of human recombinant His6x-tagged HER2 autophosphorylation expressed in Sf9 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed