BDBM50322541 CHEMBL1171085::N-{3-[2-[(Dimethylamino)methyl]-1H-imidazol-1-yl]-5-(trifluoromethyl)phenyl}-3-[2-(imidazo[1,2-a]pyridin-3-yl)ethynyl]-4-methylbenzamide

SMILES CN(C)Cc1nccn1-c1cc(NC(=O)c2ccc(C)c(c2)C#Cc2cnc3ccccn23)cc(c1)C(F)(F)F

InChI Key InChIKey=QZYXEXGJVTZDIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322541   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50322541(CHEMBL1171085 | N-{3-[2-[(Dimethylamino)methyl]-1H...)
Affinity DataIC50:  45nMAssay Description:Inhibition of wild type human ABL after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed