BDBM50322710 4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)methyl)-2-methoxyphenoxy)methyl)benzoic acid::CHEMBL1173629

SMILES COc1cc(\C=C2/SC(=O)N(Cc3ccccc3)C2=O)ccc1OCc1ccc(cc1)C(O)=O

InChI Key InChIKey=DMEMCCPBDSBSGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322710   

TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50322710(4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)me...)
Affinity DataIC50: 248nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells using bisP-nitrophenyl phosphate as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50322710(4-((4-((3-benzyl-2,4-dioxothiazolidin-5-ylidene)me...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of 6x-histidine-tagged human recombinant ATX expressed in HEK293 cells assessed as lysophosphatidulcholine releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2010
Entry Details Article
PubMed