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BDBM50322803 1-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)piperidin-4-ol::CHEMBL1173824

SMILES: OC1CCN(CC1)c1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1

InChI Key: InChIKey=NHIUBUZKCQZTGK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50322803   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aurora kinase A/Targeting protein for Xklp2


(Homo sapiens (Human))
BDBM50322803
PNG
(1-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)piperidin...)
Show SMILES OC1CCN(CC1)c1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1
Show InChI InChI=1S/C23H21N3O2/c27-18-11-13-26(14-12-18)22-20-19(16-7-3-1-4-8-16)21(17-9-5-2-6-10-17)28-23(20)25-15-24-22/h1-10,15,18,27H,11-14H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 807n/an/an/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of Aurora A


J Med Chem 53: 4980-8 (2010)

Checked by Author
Article DOI: 10.1021/jm1000198
BindingDB Entry DOI: 10.7270/Q2Z60P87
More data for this
Ligand-Target Pair