BDBM50322867 (R)-N-((R)-6-(3-(isopropylamino)prop-1-en-2-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-phenyl-3-(3-(trifluoromethyl)phenylsulfonamido)propanamide::CHEMBL1210753

SMILES CC(C)NCC(=C)c1ccc2[C@@H](CCCc2c1)NC(=O)C[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=AVACJPQOQGXSMI-LOYHVIPDSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50322867   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322867((R)-N-((R)-6-(3-(isopropylamino)prop-1-en-2-yl)-1,...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]Lys-desArg9-BK from human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50322867((R)-N-((R)-6-(3-(isopropylamino)prop-1-en-2-yl)-1,...)
Affinity DataIC50:  42nMAssay Description:Antagonist activity at human bradykinin B1 receptor assessed as inhibition of Lys-desArg9-BK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed