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BDBM50323173 (7-(2,4-dichlorophenyl)-5-methyl-2-o-tolylpyrazolo[1,5-a]pyrimidin-6-yl)methanamine::CHEMBL1209540

SMILES: Cc1ccccc1-c1cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)n2n1

InChI Key: InChIKey=FQLXYKKCRFSTOE-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323173   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50323173
PNG
((7-(2,4-dichlorophenyl)-5-methyl-2-o-tolylpyrazolo...)
Show SMILES Cc1ccccc1-c1cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)n2n1
Show InChI InChI=1S/C21H18Cl2N4/c1-12-5-3-4-6-15(12)19-10-20-25-13(2)17(11-24)21(27(20)26-19)16-8-7-14(22)9-18(16)23/h3-10H,11,24H2,1-2H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
50n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Inhibition of human DPP4


Bioorg Med Chem Lett 20: 4395-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.063
BindingDB Entry DOI: 10.7270/Q27H1JS8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50323173
PNG
((7-(2,4-dichlorophenyl)-5-methyl-2-o-tolylpyrazolo...)
Show SMILES Cc1ccccc1-c1cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)n2n1
Show InChI InChI=1S/C21H18Cl2N4/c1-12-5-3-4-6-15(12)19-10-20-25-13(2)17(11-24)21(27(20)26-19)16-8-7-14(22)9-18(16)23/h3-10H,11,24H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
5.80E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Inhibition of human DPP89


Bioorg Med Chem Lett 20: 4395-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.063
BindingDB Entry DOI: 10.7270/Q27H1JS8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50323173
PNG
((7-(2,4-dichlorophenyl)-5-methyl-2-o-tolylpyrazolo...)
Show SMILES Cc1ccccc1-c1cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)n2n1
Show InChI InChI=1S/C21H18Cl2N4/c1-12-5-3-4-6-15(12)19-10-20-25-13(2)17(11-24)21(27(20)26-19)16-8-7-14(22)9-18(16)23/h3-10H,11,24H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
7.00E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8


Bioorg Med Chem Lett 20: 4395-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.063
BindingDB Entry DOI: 10.7270/Q27H1JS8
More data for this
Ligand-Target Pair