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BDBM50323180 (2-(3-chlorophenyl)-7-(2,4-dichlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)methanamine::CHEMBL1209680

SMILES: Cc1nc2cc(nn2c(c1CN)-c1ccc(Cl)cc1Cl)-c1cccc(Cl)c1

InChI Key: InChIKey=DNKWCDIQIAAHIN-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323180   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50323180
PNG
((2-(3-chlorophenyl)-7-(2,4-dichlorophenyl)-5-methy...)
Show SMILES Cc1nc2cc(nn2c(c1CN)-c1ccc(Cl)cc1Cl)-c1cccc(Cl)c1
Show InChI InChI=1S/C20H15Cl3N4/c1-11-16(10-24)20(15-6-5-14(22)8-17(15)23)27-19(25-11)9-18(26-27)12-3-2-4-13(21)7-12/h2-9H,10,24H2,1H3
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
163n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Inhibition of human DPP4


Bioorg Med Chem Lett 20: 4395-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.063
BindingDB Entry DOI: 10.7270/Q27H1JS8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50323180
PNG
((2-(3-chlorophenyl)-7-(2,4-dichlorophenyl)-5-methy...)
Show SMILES Cc1nc2cc(nn2c(c1CN)-c1ccc(Cl)cc1Cl)-c1cccc(Cl)c1
Show InChI InChI=1S/C20H15Cl3N4/c1-11-16(10-24)20(15-6-5-14(22)8-17(15)23)27-19(25-11)9-18(26-27)12-3-2-4-13(21)7-12/h2-9H,10,24H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
5.30E+3n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Inhibition of human DPP89


Bioorg Med Chem Lett 20: 4395-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.063
BindingDB Entry DOI: 10.7270/Q27H1JS8
More data for this
Ligand-Target Pair
Dipeptidyl peptidase VIII


(Homo sapiens (Human))
BDBM50323180
PNG
((2-(3-chlorophenyl)-7-(2,4-dichlorophenyl)-5-methy...)
Show SMILES Cc1nc2cc(nn2c(c1CN)-c1ccc(Cl)cc1Cl)-c1cccc(Cl)c1
Show InChI InChI=1S/C20H15Cl3N4/c1-11-16(10-24)20(15-6-5-14(22)8-17(15)23)27-19(25-11)9-18(26-27)12-3-2-4-13(21)7-12/h2-9H,10,24H2,1H3
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
1.46E+4n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Inhibition of human DPP8


Bioorg Med Chem Lett 20: 4395-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.063
BindingDB Entry DOI: 10.7270/Q27H1JS8
More data for this
Ligand-Target Pair