BDBM50323247 6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile::CHEMBL1209086::US9115126, Reference imidazopyridine derivative from WO 2009/010491 - Example 2a

SMILES: CN(C)CCCOc1ccc(cc1C(F)(F)F)-c1cc2n(C)cnc2c(n1)C#N

InChI Key: InChIKey=CZLJABZJYZVKFX-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50323247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin S (Human)	BDBM50323247 (6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Mouse)	BDBM50323247 (6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM50323247 (6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin K (Human)	BDBM50323247 (6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	776	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM50323247 (6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM50323247 (6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin L2 (Human)	BDBM50323247 (6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Procathepsin L (Human)	BDBM50323247 (6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM50323247 (6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin K (Human)	BDBM50323247 (6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	776	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin B (Human)	BDBM50323247 (6-(4-(3-(dimethylamino)propoxy)-3-(trifluoromethyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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