BDBM50323404 1-((1-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-yl)methyl)-4-(4-methoxyphenyl)piperazine::CHEMBL1209047

SMILES COc1ccc(cc1)N1CCN(Cc2c(C)nn(c2C)-c2ccc(F)cc2)CC1

InChI Key InChIKey=NSMZLCUSUKWNNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323404   

TargetSmoothened homolog(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323404(1-((1-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-y...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by transient transfection cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50323404(1-((1-(4-fluorophenyl)-3,5-dimethyl-1H-pyrazol-4-y...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Smoothened transfected in HEK293 cells by binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed