BindingDB logo
myBDB logout

BDBM50323656 (E)-N-(5-tert-butyl-2-methoxy-3-(methylsulfonamido)phenyl)-2-(hydroxyimino)-2-(4-(2-morpholinoethoxy)naphthalen-1-yl)acetamide::CHEMBL1208831

SMILES: COc1c(NC(=O)C(N=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C

InChI Key: InChIKey=LURUQHAKRLSLQH-UHFFFAOYNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50323656   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50323656
PNG
((E)-N-(5-tert-butyl-2-methoxy-3-(methylsulfonamido...)
Show SMILES COc1c(NC(=O)C(N=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C
Show InChI InChI=1/C30H38N4O7S/c1-30(2,3)20-18-24(28(39-4)25(19-20)33-42(5,37)38)31-29(35)27(32-36)23-10-11-26(22-9-7-6-8-21(22)23)41-17-14-34-12-15-40-16-13-34/h6-11,18-19,27,33H,12-17H2,1-5H3,(H,31,35)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



K£mia, Inc.

Curated by ChEMBL


Assay Description
Inhibition of p38 alpha activity by ELISA


Bioorg Med Chem Lett 20: 4819-24 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.102
BindingDB Entry DOI: 10.7270/Q2V40W66
More data for this
Ligand-Target Pair