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BDBM50323957 (2S)-2-Amino-N-(1-(2-(2-(hydroxyamino)-2-oxoethylamino)-2-oxoethyl)-2,6-dioxopiperidin-3-yl)-3-phenylpropanamide::CHEMBL1213798

SMILES: N[C@H](Cc1ccccc1)C(=O)N[C@H]1CCC(=O)N(CC(=O)NCC(=O)NO)C1=O

InChI Key: InChIKey=UYZWRQUCKJSXPB-QWAQRTLVNA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323957   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50323957
PNG
((2S)-2-Amino-N-(1-(2-(2-(hydroxyamino)-2-oxoethyla...)
Show SMILES N[C@H](Cc1ccccc1)C(=O)N[C@H]1CCC(=O)N(CC(=O)NCC(=O)NO)C1=O
Show InChI InChI=1/C18H23N5O6/c19-12(8-11-4-2-1-3-5-11)17(27)21-13-6-7-16(26)23(18(13)28)10-15(25)20-9-14(24)22-29/h1-5,12-13,29H,6-10,19H2,(H,20,25)(H,21,27)(H,22,24)/t12-,13+/s2
PDB
MMDB

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UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.41E+5n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of MMP2 after 30 mins


Bioorg Med Chem 18: 5981-7 (2010)


Article DOI: 10.1016/j.bmc.2010.06.078
BindingDB Entry DOI: 10.7270/Q20R9PKH
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50323957
PNG
((2S)-2-Amino-N-(1-(2-(2-(hydroxyamino)-2-oxoethyla...)
Show SMILES N[C@H](Cc1ccccc1)C(=O)N[C@H]1CCC(=O)N(CC(=O)NCC(=O)NO)C1=O
Show InChI InChI=1/C18H23N5O6/c19-12(8-11-4-2-1-3-5-11)17(27)21-13-6-7-16(26)23(18(13)28)10-15(25)20-9-14(24)22-29/h1-5,12-13,29H,6-10,19H2,(H,20,25)(H,21,27)(H,22,24)/t12-,13+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.04E+5n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsome aminopeptidase N after 30 mins by UV-vis spectrophotometric analysis


Bioorg Med Chem 18: 5981-7 (2010)


Article DOI: 10.1016/j.bmc.2010.06.078
BindingDB Entry DOI: 10.7270/Q20R9PKH
More data for this
Ligand-Target Pair