BDBM50324144 CHEMBL1215328::tert-Butyl 5-Cyano-4-(2,4-difluorophenyl)-1-ethyl-2,6-dimethyl-1,4-dihydropyridine-3-carboxylate

SMILES CCN1C(C)=C(C#N)C(C(C(=O)OC(C)(C)C)=C1C)c1ccc(F)cc1F

InChI Key InChIKey=VMIHCUUPZAZFAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324144   

TargetMineralocorticoid receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324144(tert-Butyl 5-Cyano-4-(2,4-difluorophenyl)-1-ethyl-...)
Affinity DataIC50: 1.62E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed