BDBM50324149 CHEMBL1215406::Methyl 4-(2-Chlorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-propylpyridine-3-carboxylate

SMILES CCCC1=C(C(C(C#N)C(C)=N1)c1ccccc1Cl)C(=O)OC

InChI Key InChIKey=MQIWXSYBYIIVPE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324149   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324149(CHEMBL1215406 | Methyl 4-(2-Chlorophenyl)-5-cyano-...)
Affinity DataIC50:  64nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324149(CHEMBL1215406 | Methyl 4-(2-Chlorophenyl)-5-cyano-...)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at progesterone receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324149(CHEMBL1215406 | Methyl 4-(2-Chlorophenyl)-5-cyano-...)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at androgen receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324149(CHEMBL1215406 | Methyl 4-(2-Chlorophenyl)-5-cyano-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonist activity at glucocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed