BDBM50324210 (+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid::(3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid::CHEMBL1215331

SMILES OC(=O)c1ccc2C3=NN([C@@H](C4CCCC4)[C@H]3CCc2c1)c1ccc(C#N)c(Cl)c1

InChI Key InChIKey=XNULRSOGWPFPBL-REWPJTCUSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50324210   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)
Affinity DataIC50:  9nMAssay Description:Binding affinity to mineralocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)
Affinity DataIC50:  9.20nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin) by Gal4-based cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)
Affinity DataIC50:  416nMAssay Description:Antagonist activity at progesterone receptor (unknown origin) by Gal4-based cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin) by Gal4-based cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)
Affinity DataIC50: >8.91E+3nMAssay Description:Antagonist activity at androgen receptor (unknown origin) by Gal4-based cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at estrogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)
Affinity DataIC50: >8.91E+3nMAssay Description:Antagonist activity at androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)
Affinity DataIC50:  416nMAssay Description:Antagonist activity at progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed