BDBM50324334 CHEMBL1215152::Cyclohexyl-[6-piperazin-1-yl-4-(2H-pyrazol-3-yl)[2,4']bipyridinyl-2'-yl]amine

SMILES C1CCC(CC1)Nc1cc(ccn1)-c1cc(cc(n1)N1CCNCC1)-c1cc[nH]n1

InChI Key InChIKey=ZIATUPKJNZVSLT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324334   

TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324334(CHEMBL1215152 | Cyclohexyl-[6-piperazin-1-yl-4-(2H...)
Affinity DataEC50:  704nMAssay Description:Inhibition of PKD1 assessed as inhibition of HDAC5 neuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycystin-2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324334(CHEMBL1215152 | Cyclohexyl-[6-piperazin-1-yl-4-(2H...)
Affinity DataIC50:  62nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324334(CHEMBL1215152 | Cyclohexyl-[6-piperazin-1-yl-4-(2H...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed