BDBM50324416 (E)-3-(2-(3-(4-Carboxyphenyl)-6-methoxy-4-oxo-3,4-dihydroquinazolin-2-yl)vinyl)benzoic Acid::CHEMBL1215579

SMILES COc1ccc2nc(\C=C\c3cccc(c3)C(O)=O)n(-c3ccc(cc3)C(O)=O)c(=O)c2c1

InChI Key InChIKey=YBIUUOWRMKMPHR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50324416   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324416((E)-3-(2-(3-(4-Carboxyphenyl)-6-methoxy-4-oxo-3,4-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324416((E)-3-(2-(3-(4-Carboxyphenyl)-6-methoxy-4-oxo-3,4-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324416((E)-3-(2-(3-(4-Carboxyphenyl)-6-methoxy-4-oxo-3,4-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetGlutamate receptor 1(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324416((E)-3-(2-(3-(4-Carboxyphenyl)-6-methoxy-4-oxo-3,4-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed