BDBM50324604 CHEMBL1215021::N-(4-(1H-Pyrazol-4-yl)phenyl)-2-amino-3-(3-chlorophenyl)-propanamide

SMILES NC(Cc1ccc(Cl)cc1)C(=O)Nc1ccc(cc1)-c1cn[nH]c1

InChI Key InChIKey=FGYJTOWYYAFSCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324604   

TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324604(N-(4-(1H-Pyrazol-4-yl)phenyl)-2-amino-3-(3-chlorop...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50324604(N-(4-(1H-Pyrazol-4-yl)phenyl)-2-amino-3-(3-chlorop...)
Affinity DataIC50: 18nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed