BDBM50324684 3-(1-(4-amino-6-(2-fluoroacetyl)-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5,12,19-trioxo-4-oxa-6,11,18-triazahenicosan-21-yl)-5,5-difluoro-6,8-dimethyl-5,5a-dihydrocyclopenta[c]pyrrolo[1,2-f][1,2]azaborinin-4-ium-5-uide::CHEMBL1221656

SMILES C[C+]1C=C(C)C2=Cc3ccc(CCC(=O)NCCCCCC(=O)NCCCCNC(=O)OCCCn4c(C(=O)CF)c(-c5ccc(C)cc5)c5c(N)ncnc45)n3[B-](F)(F)C12

InChI Key InChIKey=DUYBUSXUFJRCHK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50324684   

TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50324684(3-(1-(4-amino-6-(2-fluoroacetyl)-5-p-tolyl-7H-pyrr...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of PMA-stimulated RSK2 phosphorylation in HEK293 cells after 1 hr by western blotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50324684(3-(1-(4-amino-6-(2-fluoroacetyl)-5-p-tolyl-7H-pyrr...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of His6-tagged RSK2 C-terminal domian expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed