BDBM50324735 (5E)-5-(QUINOXALIN-6-YLMETHYLENE)-1,3-THIAZOLIDINE-2,4-DIONE::5-(quinoxalin-6-ylmethylene)thiazolidine-2,4-dione::AS-605240::AS605240::CHEMBL568150

SMILES: c1cc2c(cc1C=C3C(=O)NC(=O)S3)nccn2

InChI Key: InChIKey=SQWZFLMPDUSYGV-UHFFFAOYSA-N

Data: 21 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50324735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein kinase CLK1 (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity tyrosine-phosphorylation-regulated kinase 2 (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.66E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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CDGSH iron-sulfur domain-containing protein 1 (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Human)	BDBM50324735 (CHEMBL568150 | AS605240 | (5E)-5-(QUINOXALIN-6-YLM...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair