BDBM50324856 7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydroxyethyl)-4-hydroxybenzo[d]thiazol-2(3H)-one::CHEMBL1221682

SMILES O[C@@H](CN[C@@H]1CCC[C@@H]1C1CCCC1)c1ccc(O)c2[nH]c(=O)sc12

InChI Key InChIKey=LMKMYJGZBLESNG-XPKDYRNWSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50324856   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324856(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]CGP12177 from human beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324856(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]iodo-(+/-)-cyanopindolol from human adrenergic beta2 receptor expressed in CHO cells after 3 hrs by radio-ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324856(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]iodo-(+/-)-cyanopindolol from human adrenergic beta1 receptor expressed in CHO cells after 3 hrs by radio-ligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324856(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]CGP12177 from human beta-1 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324856(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
Affinity DataKi:  842nMAssay Description:Displacement of [125I]7-HO-PIPAT from human D3R expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50324856(7-((R)-2-((cis)-bi(cyclopentan)-2-ylamino)-1-hydro...)
Affinity DataIC50:  0.300nMAssay Description:Agonist activity at adrenergic beta2 receptor in electrically-stimulated Dunkin-Hartley guinea pig tracheal strip assessed as inhibition of contracti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed