BDBM50325213 2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-thiadiazole::CHEMBL1223034

SMILES CC(C)(C)c1nnc(s1)-c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl

InChI Key InChIKey=KBDZMHUBIGWJPD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50325213   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50325213(2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50325213(2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of CYP2C9 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50325213(2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...)
Affinity DataIC50: >20nMAssay Description:Inhibition of CYP2D6 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50325213(2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...)
Affinity DataIC50:  1.54nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat cerebellum after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50325213(2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...)
Affinity DataIC50:  430nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50325213(2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG at holding potential of -80 mV to +40 mVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50325213(2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophe...)
Affinity DataIC50: >20nMAssay Description:Inhibition of CYP3A4 in human liver microsomes after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed