BDBM50325534 CHEMBL267495::nalfurafine

SMILES: CN([C@@H]1CC[C@]2([C@H]3Cc4ccc(c5c4[C@]2([C@H]1O5)CCN3CC6CC6)O)O)C(=O)/C=C/c7ccoc7

InChI Key: InChIKey=XGZZHZMWIXFATA-UHFFFAOYSA-N

Data: 16 KI  12 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 50325534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Rat)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
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Kappa-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0500	n/a	n/a	n/a	n/a
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Delta-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	74	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.720	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0250	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0340	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.550	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 3 (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.550	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11/12/13/14 (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rat)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.0190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Kappa-type opioid receptor (Guinea pig)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.225	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.225	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.582	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.582	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Mouse)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50325534 (nalfurafine | CHEMBL267495) Show SMILES Show InChI	GoogleScholar	UniChem		170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair