BDBM50325793 8-(3-methoxyphenyl)-6-((4-(trifluoromethyl)phenoxy)methyl)quinoline::CHEMBL1224720

SMILES COc1cccc(c1)-c1cc(COc2ccc(cc2)C(F)(F)F)cc2cccnc12

InChI Key InChIKey=RBRVHCMJYHPWCS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50325793   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325793(8-(3-methoxyphenyl)-6-((4-(trifluoromethyl)phenoxy...)
Affinity DataIC50:  218nMAssay Description:Inhibition of human PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325793(8-(3-methoxyphenyl)-6-((4-(trifluoromethyl)phenoxy...)
Affinity DataIC50:  418nMAssay Description:Inhibition of human PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325793(8-(3-methoxyphenyl)-6-((4-(trifluoromethyl)phenoxy...)
Affinity DataIC50:  338nMAssay Description:Inhibition of human PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50325793(8-(3-methoxyphenyl)-6-((4-(trifluoromethyl)phenoxy...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed