BDBM50325878 CHEMBL1224213::endo-2-((1R,5S)-8-benzyl-8-azabicyclo[3.2.1]octan-3-yloxy)benzamide

SMILES NC(=O)c1ccccc1O[C@@H]1C[C@@H]2CC[C@H](C1)N2Cc1ccccc1

InChI Key InChIKey=VZUNLOUVARCFRX-PIIMJCKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325878   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325878(CHEMBL1224213 | endo-2-((1R,5S)-8-benzyl-8-azabicy...)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in HEK cells assessed as inhibition of dynorphin A-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50325878(CHEMBL1224213 | endo-2-((1R,5S)-8-benzyl-8-azabicy...)
Affinity DataIC50:  340nMAssay Description:Inhibition of human ERG by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed