BDBM50325946 CHEMBL1223710::N-(3-(1-(3-(1-phenyl-1H-benzo[d]imidazol-2-ylamino)propyl)piperidin-4-yl)phenyl)acetamide

SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCNc2nc3ccccc3n2-c2ccccc2)CC1

InChI Key InChIKey=KQIUBTAVIPAELX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325946   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50325946(CHEMBL1223710 | N-(3-(1-(3-(1-phenyl-1H-benzo[d]im...)
Affinity DataIC50:  153nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHOK1 cells assessed as reduction in [3H]inositol phosphate levels by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50325946(CHEMBL1223710 | N-(3-(1-(3-(1-phenyl-1H-benzo[d]im...)
Affinity DataIC50:  21nMAssay Description:Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHOK1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed