BDBM50325978 CHEMBL1224387::ethyl 4-(1-(4-(1-(4-fluorophenyl)-1H-benzo[d]imidazol-2-yl)butyl)piperidin-4-yl)-2-hydroxybenzoate

SMILES CCOC(=O)c1ccc(cc1O)C1CCN(CCCCc2nc3ccccc3n2-c2ccc(F)cc2)CC1

InChI Key InChIKey=CYYGNFHTNGYTMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325978   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50325978(CHEMBL1224387 | ethyl 4-(1-(4-(1-(4-fluorophenyl)-...)
Affinity DataIC50:  566nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHOK1 cells assessed as reduction in [3H]inositol phosphate levels by scintillation proxi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50325978(CHEMBL1224387 | ethyl 4-(1-(4-(1-(4-fluorophenyl)-...)
Affinity DataIC50:  566nMAssay Description:Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHOK1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed