BDBM50326053 CHEMBL608533::PKC-412::US20240132489, Compound Staurosporine

SMILES: C[C@@]12[C@@H]([C@@H](C[C@@H](O1)n3c4ccccc4c5c3c6n2c7ccccc7c6c8c5C(=O)NC8)N(C)C(=O)c9ccccc9)OC

InChI Key: InChIKey=BMGQWWVMWDBQGC-UHFFFAOYSA-N

Data: 35 IC50  1127 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1170 hits for monomerid = 50326053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-H/Cyclin-dependent kinase 7 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	797	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	32.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-T1/Cyclin-dependent kinase 9 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-K/Cyclin-dependent kinase 12 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase receptor TYRO3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	528	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Casein kinase I isoform epsilon (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity protein kinase CLK1 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity protein kinase CLK2 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity protein kinase CLK4 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	887	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity tyrosine-phosphorylation-regulated kinase 2 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 4 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glycogen synthase kinase-3 beta (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Epidermal growth factor receptor (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	528	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	418	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	662	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	283	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK4 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 15 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 4 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK4 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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cGMP-dependent protein kinase 1 (Human)	BDBM50326053 (PKC-412 | CHEMBL608533 | US20240132489, Compound S...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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