BDBM50326090 (E)-2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitrophenyl)-1-(4-(4-(2-hydroxy-ethyl)piperazine-1-carbonyl)phenyl)prop-2-en-1-one::CHEMBL1242391

SMILES OCCN1CCN(CC1)C(=O)c1ccc(cc1)C(=O)C(\SCc1ccc(Br)cc1)=C/c1ccc(F)c(c1)[N+]([O-])=O

InChI Key InChIKey=AATUFOXFWPLFGG-OVVQPSECSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326090   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50326090((E)-2-(4-Bromobenzylthio)-3-(4-fluoro-3-nitropheny...)
Affinity DataIC50:  500nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed