BDBM50326097 (S)-3-((S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-methylbutanamido)-5-(methylsulfonyl)pent-4-enoic acid::CHEMBL1242886

SMILES CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](CC(O)=O)C=CS(C)(=O)=O

InChI Key InChIKey=JRNVXXWCJAJTSN-OSPHWJPCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326097   

TargetCaspase-7(Homo sapiens (Human))
University Of Lisbon

Curated by ChEMBL
LigandPNGBDBM50326097((S)-3-((S)-2-(((9H-fluoren-9-yl)methoxy)carbonylam...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human recombinant caspase 7 assessed as fluorescent 7-amido-4-methylcoumarin releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Lisbon

Curated by ChEMBL
LigandPNGBDBM50326097((S)-3-((S)-2-(((9H-fluoren-9-yl)methoxy)carbonylam...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human recombinant caspase-3 expressed in Saccharomyces cerevisiae CG379 assessed as growth stimulation after 2 daysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
University Of Lisbon

Curated by ChEMBL
LigandPNGBDBM50326097((S)-3-((S)-2-(((9H-fluoren-9-yl)methoxy)carbonylam...)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibition of human recombinant caspase 3 assessed as fluorescent 7-amido-4-methylcoumarin releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed