BDBM50326189 (E)-6-Hydroxy-9-methoxy-11H-indeno[1,2-c]quinolin-11-one O-2-(Piperidin-1-yl)ethyl Oxime::CHEMBL1243230

SMILES COc1ccc-2c(c1)\C(=N/OCCN1CCCCC1)c1c-2c(=O)[nH]c2ccccc12

InChI Key InChIKey=VFTKFZSHUCTNDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326189   

TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandPNGBDBM50326189((E)-6-Hydroxy-9-methoxy-11H-indeno[1,2-c]quinolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed